| 2025-08-26 19:00:17August 26, 2025 | Owen J. Roberts Varsity vs Downingtown East Varsity | 1 – 1 | |
| 2025-08-28 15:45:32August 28, 2025 | Conestoga HS Varsity vs Downingtown East Varsity | 1 – 0 | |
| 2025-09-02 16:00:43September 2, 2025 | Villa Joseph Marie Varsity vs Downingtown East Varsity | 1 – 3 | |
| 2025-09-04 16:15:43September 4, 2025 | Manheim Township Varsity vs Downingtown East Varsity | 3 – 0 | |
| 2025-09-08 15:45:55September 8, 2025 | Unionville HS Varsity vs Downingtown East Varsity | 0 – 2 | |
| 2025-09-10 19:00:01September 10, 2025 | West Chester Henderson HS Varsity vs Downingtown East Varsity | 0 – 3 | |
| 2025-09-16 15:45:06September 16, 2025 | Avon Grove HS Varsity vs Downingtown East Varsity | 0 – 1 | |
| 2025-09-18 19:00:54September 18, 2025 | Coatesville Area HS Varsity vs Downingtown East Varsity | 1 – 2 | |
| 2025-09-22 15:45:48September 22, 2025 | West Chester East HS Varsity vs Downingtown East Varsity | 0 – 5 | |
| 2025-09-24 19:00:37September 24, 2025 | West Chester Rustin HS Varsity vs Downingtown East Varsity | 1 – 0 | |
| 2025-09-27 10:00:27September 27, 2025 | Perkiomen Valley Varsity vs Downingtown East Varsity | 0 – 1 | |
| 2025-09-30 15:45:29September 30, 2025 | Sun Valley HS Varsity vs Downingtown East Varsity | 0 – 9 | |
| 2025-10-01 15:45:22October 1, 2025 | Bishop Shanahan Varsity vs Downingtown East Varsity | 0 – 3 | |
| 2025-10-03 15:45:28October 3, 2025 | Garnet Valley HS Varsity vs Downingtown East Varsity | 1 – 1 | |
| 2025-10-06 19:00:13October 6, 2025 | Downingtown West HS Varsity vs Downingtown East Varsity | 2 – 0 | |
| 2025-10-08 19:00:36October 8, 2025 | Kennett HS Varsity vs Downingtown East Varsity | 0 – 1 | |
| 2025-10-14 15:45:04October 14, 2025 | Oxford Area HS Varsity vs Downingtown East Varsity | 0 – 9 | |
| 2025-10-16 15:45:47October 16, 2025 | Great Valley Varsity vs Downingtown East Varsity | 0 – 1 | |
